All in all, that’s one nightcap to avoid. Topical medicine is for use only on the skin. And mixing certain antibiotics with alcohol—specifically metronidazole, tinidazole, and trimethoprim-sulfamethoxazole—can be downright dangerous. If you’re taking any type of blood clot medication, it’s important to note that even occasional drinking (think: a glass of wine with dinner a few times per week) can lead to internal bleeding. Including brand-name drugs like: Depakene, Depakote, Eskalith, Lithate, Lithobid, Valproic. Alcohol, Heroin and Crack—in That Order TIME – Catherine Mayer. For example, when alcohol is combined with some antihistamines, like diphenhydramine (Benadryl) that normally causes drowsiness as a side effect, the drowsiness may be magnified. According to the National Institute for Alcohol Abuse and Alcoholism, prescription-strength painkillers and opioids, This Is Your Body On Alcohol (Infographic), 4 Ways To Prevent A Common Medication Mix-Up. Drugs without any apparent medical utility are automatically placed in the most dangerous category—and subjected to the strictest criminal penalties—regardless of the risk they pose. Alcohol, like some medi-cines, can make you sleepy, drowsy, or lightheaded. The danger is real. The effects of the mix can be especially serious—if not deadly—when the cough medicine also contains alcohol. Including brand-name drugs like: Advil, Motrin, Tylenol, Aleve. “So it has the potential to interact with a whole host of drugs, including things you might not think are related at all.”. Can the COVID-19 Vaccine Cause Allergic Reactions? If you do choose to drink a moderate amount, do so in a safe setting, in which you don’t have to drive or otherwise put yourself at risk. Offers may be subject to change without notice. When mixed with booze, cholesterol medications can cause liver damage. Over-the-counter allergy remedies like Benadryl and Zyrtec contain antihistamines, a class of drug that can cause excessive drowsiness and may put you at risk if you’re driving a car or operating machinery—even more so when you’ve also had a drink or two. 3 If that’s the case for you, be sure to avoid alcohol. Plus, doing so can be dangerous. Even though those drugs have highly addictive properties and the ability to ruin lives and negatively impact societies, none of those substances make the top entry for the most dangerous drugs in the world. Of course, some potential interactions are more worrisome than others. The NIAAA also notes that alcohol can increase side effects of nitroglycerin including dizziness, lightheadedness, and fainting. © Copyright 2021 Meredith Corporation. If you manage your high blood pressure with prescription medication, saying no to alcohol is extremely important. 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"Alcohol can either inhibit or amplify the effects of the medication in an uncontrolled and unpredictable way," says Kristine Arthur, MD, an internist at MemorialCare Orange Coast Medical Center in Fountain Valley, California.That’s true for both over-the-counter and prescription medications—and even mixing alcohol with natural remedies, like St. John’s Wort, can be problematic. Alcohol is a common cause of heartburn, sour stomach,and indigestion, so you probably don't want to head to happy hour if you're experiencing any of these issues. Or, you might try Phenergan, which can also be used to manage nausea and vomiting that may occur post-surgery, according to the NIH. Mixing alcohol with certain medications can cause nausea and vomiting, headaches, drowsiness, fainting, or loss of coordination. But here’s the kicker: The risk of these potentially severe side effects increases when you drink alcohol, according to the NIH, especially for older adults and those who are already in poor health. Alcohol often has harmful interactions with prescription medications, over-the-counter drugs, and even some herbal remedies. Alcohol is the world's most dangerous drug when you consider the harm it does to drinkers, their friends and families, and society in general. From over-the-counter allergy meds to prescription sleeping pills and everything in between, here are some of the scary consequences that can result if you ignore that alcohol warning on a pill bottle. A Top Neurosurgeon’s Best Tips for Brain Health, Meghan McCain Shares First Photo of Her Daughter, Buddy Valastro Made a Huge Cake for Hospital Staff. "I'm petrified," the actress said when she shared the news that her breast cancer came back. In fact, more Americans die of drug overdoses than in car accidents each year. If you turn to herbal remedies, like a soothing cup of chamomile or lavender tea, and accompany it with alcohol, you may feel extra drowsy. Drinking can cause arrhythmia or a change in your heartbeat. In light of these staggering statistics, 24/7 Wall St. recently conducted a new study that reviewed and categorized 25 of the most dangerous drugs and drug mixtures. Another side effect worth noting: Drinking while taking Focalin, Concerta, or Ritalin, can actually result in impaired concentration—the exact reverse of the medication’s purpose. Drug overdoses are now the leading cause of accidental death in the United States. The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments. QUIZ: How Much Do You Know About Alcohol? Doing so can result in abnormally low blood sugar levels, nausea, vomiting, headaches, a rapid heartbeat, or a sudden change in blood pressure, according to the NIAAA. Here's why a stage 4 breast cancer diagnosis can be so frightening. If you drink while taking Glucophage (generic: metformin), you may also experience feelings of weakness. This combination can cause an overdose which may be fatal. You … Apply a small amount of this product to your skin using a clean cotton ball, cotton swab, or cotton gauze. These drugs include commonly known medications, such as alprazolam (Xanax), chlordiazepoxide (Librium), diazepam (Valium), and lorazepam (Ativan), as well as clonazepam (Klonopin), oxazepam (Serax), and temazepam (Restoril). Including brand-name drugs like: Adderall, Ritalin, Focalin, Dexedrine, Strattera, Concerta. Bottom line: Raise a glass and enjoy alcohol in moderation, says Rech. One ingredient in some cough suppressants called dextromethorphan (DXM) can be especially dangerous because it can cause extreme sedation and respiratory depression. Prescription drug abuse can increase the risk of experiencing the adverse side effects of alcohol. Over-the-counter medications to prevent or treat these tummy troubles can increase the inebriating effects of alcohol and can also result in a rapid heart rate or a sudden change in your blood pressure—two things that can cause dizziness and fainting spells, the NIAAA cautions. Researches of Abbott—Vital Resistance lowered by alcohol—Experiments upon Urinary Toxicity—Effect of alcohol upon the guardian-cells of the body—Dr. Prevention participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. 1. Why I Insisted on Getting a Mammogram at 35, 20 Medications You Should Never Mix With Alcohol. Another family of antibiotics, known as cephalosporins, can also cause similar reactions, says Rech. Not sure what class of drug you’re taking? Even though it is the deadliest drug, alcohol is legal in the U.S. and Britain, as well as many other countries around the world. But over-the-counter pain medications should be taken with care. Nothing good. Clean out expired products and clutter to make way for a healthier you. And then there’s acetaminophen (Tylenol), which has a direct effect on the liver—an organ that’s even more at risk from excessive drinking. Here are the ones you need to pay attention to, and how to know if you may have an anxiety disorder. If you’ve ever turned down a happy hour invite because you’re on antibiotics, you probably know that alcohol and medication can be a bad, even dangerous combination. Accompany these medications with rest and physical therapy—not cocktails. Some cold-and-flu formulas also contain acetaminophen, as well—all the more reason not to mix them with beer, wine, or liquor. One type of antidepressant—monoamine oxidase inhibitors (MAOIs)—can cause heart problems and dangerously high blood pressure when combined with booze. Including brand-name drugs like: Isordil, Nitrostat, Rectiv, Nitrolingual. These beverages contain a byproduct that when consumed with MAOIs can increase the risk of high blood pressure. There are certain types of over-the-counter drugs that do not mix with alcohol. Why? Both classes of drugs share some additional risks when combined with alcohol. Another common and dangerous drug and alcohol combination is alcohol and prescription painkillers such as Oxycodone. Antihistamines are also used in some cold and flu medicines, like NyQuil, and in some nighttime sleep aids like ZzzQuil. Drinking while taking Flomax (generic: tamsulosin) or other drugs prescribed for an enlarged prostate, could lead to feeling dizzy or lightheaded, or even fainting. (Unless you’re on MAIOs, she adds; then you should avoid alcohol completely. Mixing alcohol and other drugs together can lead to serious physical, behavioral and health complications. Reasons Why Alcohol Is Dangerous as Medicine. DID YOU KNOW… Mixing alcohol and medicines can be harmful. Your pharmacist or other health care provider can help you determine which medications interact harmfully with alcohol. Combining them with alcohol can lead to dizziness and drowsiness. “That’s reason enough to use alcohol sparingly while your body is healing.”. Health.com is part of the Meredith Health Group. Side effects may worsen if you drink alcohol and take one of these drugs along with an antidepressant. And that’s not a good thing: Even one drink can cause drowsiness, dizziness, and slowed breathing when taken with another sedative. "Mixing antidepressants such as selective serotonin reuptake inhibitors with alcohol can impair motor function and suppress breathing as well as cause unusual behavior," says Dr. Arthur. Alcohol can also keep your antidepressant from working as well as it should, and can make your underlying depression worse. But be warned: Do not drink while taking these drugs. The Top 15 Most Dangerous Drugs. Your doctor will likely warn you about drinking when you’re prescribed antibiotics, and for good reason. But that’s not all. Drinking while on valproic acid can also lead to liver damage, the NIAAA points out. Alcohol withdrawal is common, but delirium tremens only occurs in 5% of people who have alcohol withdrawal. How to handle a physician who doubts or dismisses your symptoms. But the danger of mixing drugs, supplements, and/or alcohol is very real. Here’s Rech’s advice on drinking when you’re taking any of these common meds. Drinking while you are taking prescription-strength painkillers and opioids can result in a laundry list of unpleasant side effects, including an increased risk of overdose, impaired motor control, memory problems, and unusual behavior. It also increases your risk of experiencing these medications’ side effects including restlessness, loss of appetite, depression, and impaired motor control. From easier cramps to a heavier flow, here's a guide on what to expect decade by decade. As we can see from this study and alcohol’s far-reaching effects, legal substances cause just as much damage, or more, than illegal substances. "Mixing alcohol and medication for chest pain like nitroglycerin [the generic name for Nitrostat, Rectiv, and Nitrolingual]...can cause dangerously low blood pressure or … Valproic (generic: valproic acid), which treats seizures as well as mania, is another. Most medications cause minor side effects on their own, but alcohol can amplify the effects. The harm that alcohol does exceeds the dangers of even heroin and crack cocaine when the overall danger to the user and others is taken into account. Bottom line: If you’re otherwise healthy, having one or two drinks before or after taking an NSAID shouldn’t be the end of the world. According to the National Institute for Alcohol Abuse and Alcoholism (NIAAA), mixing over-the-counter sniffle stoppers with booze can leave you feeling drowsy or dizzy. "Any antihistamines—the class of medication [that combats allergies]—that are associated with drowsiness can have more of an effect of sedating with alcohol," says Dr. Andrew Weinstein, a board-certified allergist and clinical immunologist, and Associate Clinical Professor of Pediatrics at Thomas Jefferson Medical College. Even antihistamines that are advertised as non-drowsy (such as Claritin and Allegra) can have this effect in some people, says Rech, especially when paired with alcohol. Overdose symptoms might include breathing problems, blurred vision, coma, constipation, seizures, nausea, and vomiting, among other things, according to the NIH. Including brand-name drugs like: Reglan, Zantac, Tagamet, Maalox, Rolaids, Nexium, Prilosec. There are basically two types of drug interactions with alcohol. That depends on the medication in question—and on other factors like your medical history, says Megan Rech, an emergency medicine clinical pharmacist at Loyola University Medical Center. Combine alcohol with prescription treatments like Lunesta or Ambien, and you may feel unusually drowsy, sleepy, and dizzy. For example, a medication like Tylenol is safe for most people in low doses. Long-term use of nonsteroidal anti-inflammatory medicines, including over-the-counter painkillers like ibuprofen (Advil) and naproxen (Aleve), can increase your risk of stomach bleeding and ulcers; adding alcohol can make these side effects even more likely. If you’re taking medication to manage arthritis pain, you should know that all of these medications are strong non-steroidal anti-inflammatory drugs (NSAIDs), and as such, can cause ulcers, stomach bleeding, or liver damage. Many medications can cause problems when taken with alcohol — including anti-anxiety medications, sleep medications and prescription pain medications. Bottom line: Don’t drink if you’re taking one of the antibiotics listed above, or for 72 hours after your last dose, says Rech. The NIAA notes that drinking while taking muscle relaxants can also lead to an increased risk of seizures, impaired motor control, unusual behavior, and memory problems. In some cases, benzodiazepines and even barbiturates may be prescribed for seizure control; however, the effects of alcohol with these two classes of drugs will be explained below. Consuming alcohol while taking lithium or valproic acid can also cause drowsiness, dizziness, and tremors. Not only can drinking and drugs increase the effects of each substance, it can also trigger dangerous interactions. The problem with that is aging slows down the body’s ability to metabolize alcohol… Including brand-name drugs like: Coumadin, Eliquis, Bevyxxa, Pradaxa. The NIAA lists rapid heartbeat and sudden change in blood pressure as potential reactions to mixing the medication with alcohol, Including brand name drugs like: Ativan, Xanax, Librium, Valium. "While the effects of alcohol on virtually all classes of medication can be dangerous, what is scarier is the unpredictability," he notes.Fortunately, we can anticipate some of the potential side effects that can occur when you imbibe while on medications. (For women, that’s no more than one serving a day.) If you’re one of many Americans with high cholesterol, you might be managing it with the help of a medication like Lipitor (generic: atorvastatin). Most alarming, almost 80 percent of people 65 and older who imbibed combined alcohol with dangerous drugs. When a medication side effect like drowsiness is magnified by the use of alcohol it is called an additive effect. Including brand-name drugs like: Mucinex, Robitussin Chest Congestion. Alcohol can make some of the unpleasant side effects of these drugs, like upset stomach and dizziness, worse than normal. Many pill bottles warn that individuals taking the medication should limit or avoid alcohol intake. "Even a single large dose of an opioid can cause severe respiratory depression (slowing or stopping of breathing), which can be fatal; taking opioids with alcohol or sedatives increases this risk," the NIH cautions. Cholesterol medications, on the other hand, are metabolized in the liver, which can lead to liver damage and bleeding if you’re drinking frequently or excessively. Most antidepressants out there fall into two classes: selective serotonin reuptake inhibitors (SSRIs) or Monoamine oxidase inhibitors (MAOIs). The Most Dangerous Drugs? Heavier drinking may also cause internal bleeding, as well as blood clots, stroke, or heart attack, the NIAAA warns. All rights reserved. And mixing certain antibiotics with alcohol—specifically metronidazole, tinidazole, and trimethoprim-sulfamethoxazole—can be downright dangerous. For example, opioid medications are classified as sedative drugs, meaning that they suppress the central nervous system and contribute to the slowing of many bodily functions. But when it’s combined with alcohol or taken in high doses, Tylenol can cause serious liver damage. “Alcohol is metabolized in the liver, and a lot of drugs are metabolized via the same pathways,” Rech says. That's silly. Prescription medications for attention-deficit/hyperactivity disorder are considered central nervous system stimulants. There’s a reason why prescription medication packages are marked with a “DO NOT MIX WITH ALCOHOL” label—it’s dangerous. “Medicines for hypertension work by lowering blood pressure, but alcohol can have an additive effect and make blood pressure drop too low, causing dizziness or fainting,” she says. Including brand-name drugs like: Antivert, Dramamine, Phenergan. Mixing medicine and alcohol can have all kinds of negative side effects. 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