"I'm petrified," the actress said when she shared the news that her breast cancer came back. 1.1. Including brand-name drugs like: Flomax, Uroxatral, Cardura, Minipress, Rapaflo. Not only can drinking and drugs increase the effects of each substance, it can also trigger dangerous interactions. Never take Tylenol after a night of drinking to prevent a hangover," Dr. Arthur adds. And an anxiety or sleep medication which calms you could make you stop breathing," says David Cutler, MD, a family medicine physician at Providence Saint John’s Health Center in Santa Monica, California. Over-the-counter allergy remedies like Benadryl and Zyrtec contain antihistamines, a class of drug that can cause excessive drowsiness and may put you at risk if you’re driving a car or operating machinery—even more so when you’ve also had a drink or two. In general, though, it’s smart to assume that even a tiny bit of booze can affect a drug’s safety and effectiveness. Apply a small amount of this product to your skin using a clean cotton ball, cotton swab, or cotton gauze. "Mixing alcohol and medication for chest pain like nitroglycerin [the generic name for Nitrostat, Rectiv, and Nitrolingual]...can cause dangerously low blood pressure or abnormal heart rhythms," Dr. Arthur says. Dr. Arthur echos these warnings, adding that mixing alcohol with blood thinners can also increase or decrease the thickness of the blood and can cause dangerous bleeding or hemorrhage. But over-the-counter pain medications should be taken with care. Here’s Rech’s advice on drinking when you’re taking any of these common meds. "Cyclobenzaprine can make the effects of alcohol worse," the NIH says, and can also leave patients feeling drowsy. Both classes of drugs share some additional risks when combined with alcohol. Alcohol often has harmful interactions with prescription medications, over-the-counter drugs, and even some herbal remedies. "While the effects of alcohol on virtually all classes of medication can be dangerous, what is scarier is the unpredictability," he notes.Fortunately, we can anticipate some of the potential side effects that can occur when you imbibe while on medications. Antihistamines are also used in some cold and flu medicines, like NyQuil, and in some nighttime sleep aids like ZzzQuil. Drinking while on valproic acid can also lead to liver damage, the NIAAA points out. “So it has the potential to interact with a whole host of drugs, including things you might not think are related at all.”. Your pharmacist or other health care provider can help you determine which medications interact harmfully with alcohol. Another common and dangerous drug and alcohol combination is alcohol and prescription painkillers such as Oxycodone. Acetaminophen by itself can lead to overdose… QUIZ: How Much Do You Know About Alcohol? 1 . Lithate and Lithobid (generic: lithium) are antimanic agents prescribed to both treat and prevent manic episodes in people with bipolar disorder. If you do choose to drink a moderate amount, do so in a safe setting, in which you don’t have to drive or otherwise put yourself at risk. Topical medicine is for use only on the skin. “If you’re on antibiotics, you have some sort of acute bacterial infection,” says Rech. "Both work centrally in your brain to depress your respiratory center,” says Rech. Here's What to Do, 9 Signs It's More Serious Than the Common Cold, How Your Period Changes During Your 20s, 30s, and 40s, 12 Anxiety Symptoms That Might Point to a Disorder, Shannen Doherty Reveals Stage 4 Breast Cancer Diagnosis—Here's What It Means, The Best (and Worst) Diets of 2020, According to Experts, 10 Moves for a Cardio Workout at Home—No Equipment Required, These 13 Women Prove Every Body Is a Bikini Body, 20 Things You Should Throw Away for Better Health, If You're Taking an Antidepressant for a Reason Besides Depression, You Should Read This, How to get Birth Control Without a Doctor's Appointment. Credit: 3 Open mobile menu And mixing certain antibiotics with alcohol—specifically metronidazole, tinidazole, and trimethoprim-sulfamethoxazole—can be downright dangerous. Research shows that alcohol consumption can impair reaction times and decision-making at blood-alcohol levels lower than the 0.08 legal intoxication level at 0.05 BAC. Mixing diabetes medication with alcohol is never a good idea. Do not use isopropyl alcohol on open wounds or on sunburned, windburned, dry, chapped, or irritated skin. But when it’s combined with alcohol or taken in high doses, Tylenol can cause serious liver damage. Even antihistamines that are advertised as non-drowsy (such as Claritin and Allegra) can have this effect in some people, says Rech, especially when paired with alcohol. Your doctor will likely warn you about drinking when you’re prescribed antibiotics, and for good reason. But when doctors say not to mix drinking with drugs, are they really talking about one beer or glass of wine? The NIAAA also notes that alcohol can increase side effects of nitroglycerin including dizziness, lightheadedness, and fainting. Drinking while taking Flomax (generic: tamsulosin) or other drugs prescribed for an enlarged prostate, could lead to feeling dizzy or lightheaded, or even fainting. If you’re one of many Americans with high cholesterol, you might be managing it with the help of a medication like Lipitor (generic: atorvastatin). Mixing alcohol with benzodiazepines—drugs that help relieve anxiety and panic attacks—can result in life-threatening symptoms. "Any antihistamines—the class of medication [that combats allergies]—that are associated with drowsiness can have more of an effect of sedating with alcohol," says Dr. Andrew Weinstein, a board-certified allergist and clinical immunologist, and Associate Clinical Professor of Pediatrics at Thomas Jefferson Medical College. But don’t make it a habit, and be careful not to overdose on either. Three drugs have FDA approval for alcohol use disorder, and each works differently. But that’s not all. The danger is real. But here’s the kicker: The risk of these potentially severe side effects increases when you drink alcohol, according to the NIH, especially for older adults and those who are already in poor health. Alcohol and warfarin side effects: When warfarin is combined with alcohol, the effects of warfarin can be altered and may lead to a greater risk of bleeding or a decreased warfarin effect. According to the National Institute for Alcohol Abuse and Alcoholism, prescription-strength painkillers and opioids, This Is Your Body On Alcohol (Infographic), 4 Ways To Prevent A Common Medication Mix-Up. For example, a medication like Tylenol is safe for most people in low doses. Many pill bottles warn that individuals taking the medication should limit or avoid alcohol intake. "Even a single large dose of an opioid can cause severe respiratory depression (slowing or stopping of breathing), which can be fatal; taking opioids with alcohol or sedatives increases this risk," the NIH cautions. Including brand-name drugs like: Diabinese, Glucophage, Orinase. One type of antidepressant—monoamine oxidase inhibitors (MAOIs)—can cause heart problems and dangerously high blood pressure when combined with booze. Alcohol, Heroin and Crack—in That Order TIME – Catherine Mayer. 13  Treating an infection with prescription medication? “That’s reason enough to use alcohol sparingly while your body is healing.”. For example, when alcohol is combined with some antihistamines, like diphenhydramine (Benadryl) that normally causes drowsiness as a side effect, the drowsiness may be magnified. Doing so can result in abnormally low blood sugar levels, nausea, vomiting, headaches, a rapid heartbeat, or a sudden change in blood pressure, according to the NIAAA. "A cold pill that makes you a little drowsy could make you unconscious mixed with alcohol. Drinking while you are taking prescription-strength painkillers and opioids can result in a laundry list of unpleasant side effects, including an increased risk of overdose, impaired motor control, memory problems, and unusual behavior. Bottom line: Don’t drink if you’re taking one of the antibiotics listed above, or for 72 hours after your last dose, says Rech. Chronic alcohol abuse can elevate the risk for liver disease, such as cirrhosis. A recent scientific study found that the most dangerous drug happens to be alcohol. And then there’s acetaminophen (Tylenol), which has a direct effect on the liver—an organ that’s even more at risk from excessive drinking. The harm that alcohol does exceeds the dangers of even heroin and crack cocaine when the overall danger to the user and others is taken into account. But what happens if you ignore that warning? Drinking can cause arrhythmia or a change in your heartbeat. The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments. Mixing medicine and alcohol can have all kinds of negative side effects. Bottom line: “If your depression is well managed, then it’s probably okay to have an occasional alcoholic beverage while you’re on medication,” says Rech. Most medications cause minor side effects on their own, but alcohol can amplify the effects. Prevention participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. There are basically two types of drug interactions with alcohol. Springtime sniffles may have you reaching for allergy meds, which are known for interacting poorly with alcohol. If you strain a muscle at the gym or get a particularly bad charley horse, your doctor may prescribe Flexeril (generic name: cyclobenzaprine) or Soma (generic name: carisoprodol). Mixing alcohol with certain medications can cause nausea and vomiting, headaches, drowsiness, fainting, or loss of coordination. Reasons Why Alcohol Is Dangerous as Medicine. Offers may be subject to change without notice. If that’s the case for you, be sure to avoid alcohol. From over-the-counter allergy meds to prescription sleeping pills and everything in between, here are some of the scary consequences that can result if you ignore that alcohol warning on a pill bottle. Even though those drugs have highly addictive properties and the ability to ruin lives and negatively impact societies, none of those substances make the top entry for the most dangerous drugs in the world. Can the COVID-19 Vaccine Cause Allergic Reactions? Individuals who abuse alcohol are also more likely to abuse other substances, like prescription or illicit drugs. If you’re taking any type of blood clot medication, it’s important to note that even occasional drinking (think: a glass of wine with dinner a few times per week) can lead to internal bleeding. Is Your Doctor Gaslighting You? Drinking while you're taking a prescription or OTC medication may not seem like a big deal. The NIAA notes that drinking while taking muscle relaxants can also lead to an increased risk of seizures, impaired motor control, unusual behavior, and memory problems. Unfortunately, many people overlook this. Both are problematic when mixed with alcohol, and can cause drowsiness, dizziness, or increased feelings of depression or hopelessness. Including brand-name drugs like: Mucinex, Robitussin Chest Congestion. As we can see from this study and alcohol’s far-reaching effects, legal substances cause just as much damage, or more, than illegal substances. Alcohol is a common cause of heartburn, sour stomach,and indigestion, so you probably don't want to head to happy hour if you're experiencing any of these issues. The effects of the mix can be especially serious—if not deadly—when the cough medicine also contains alcohol. That's silly. My "Gray Area" Drinking Spiraled Into Alcoholism, 14 Lowest Calorie Alcoholic Drinks You'll Love, 5 Tips for Taking Chronic-Condition Medication. That depends on the medication in question—and on other factors like your medical history, says Megan Rech, an emergency medicine clinical pharmacist at Loyola University Medical Center. Doctors explain how to tell if you have a head cold or something more serious that requires medical attention, such as the flu, strep throat, meningitis, or mono. There’s a reason why prescription medication packages are marked with a “DO NOT MIX WITH ALCOHOL” label—it’s dangerous. Delirium tremens is dangerous, killing as many as 1 out of every 20 people who develop its symptoms.After withdrawal is complete, it is essential that you not begin drinking again. Including brand-name drugs like: Advil, Motrin, Tylenol, Aleve. Not sure what class of drug you’re taking? Why? "Stimulant drugs like those for ADHD...can have wildly activating effects when mixed with alcohol," says Dr. Cutler. From easier cramps to a heavier flow, here's a guide on what to expect decade by decade. RELATED: 13 Drugs That Can Make You Gain Weight. This combination can cause an overdose which may be fatal. Be cautious about imbibing too much—which can not only cloud your judgment, but could also lead to vomiting up a recently taken pill. Nothing good. For those who suffer from polydrug addictions, however, medical detox can be more complicated than for single drug addictions. But the NIAAA also cautions that combining these prescription-strength sleep aids with alcohol could also lead to impaired motor control, unusual behavior, memory problems, and slowed or difficult breathing. Those side effects may not seem so serious when you’re aiming to head to dreamland anyway. And no matter what medication regimen you’re on, don’t drink more than moderate amounts. Some medications, for example duloxetine (Cymbalta, Irenka) may also cause liver damage. Alcohol is the world's most dangerous drug when you consider the harm it does to drinkers, their friends and families, and society in general. All rights reserved. "Mixing antidepressants such as selective serotonin reuptake inhibitors with alcohol can impair motor function and suppress breathing as well as cause unusual behavior," says Dr. Arthur. Alcohol withdrawal is common, but delirium tremens only occurs in 5% of people who have alcohol withdrawal. Alcohol makes the effects of sleeping pills—both over-the-counter and prescription varieties—stronger. Here's why a stage 4 breast cancer diagnosis can be so frightening. These drugs contain enzymes that react with alcohol and can cause headache, flushing, a rapid heartbeat, nausea, and vomiting. Prescription medications for attention-deficit/hyperactivity disorder are considered central nervous system stimulants. Heavier drinking may also cause internal bleeding, as well as blood clots, stroke, or heart attack, the NIAAA warns. "Mixing alcohol with common over the counter anti-inflammatory pain medications like ibuprofen and Naprosyn can cause GI upset, ulcers, and even stomach bleeding," says Dr. Arthur. People who take drugs for a cardiovascular condition should be cautious about drinking alcohol, says Rech. Consuming alcohol while taking lithium or valproic acid can also cause drowsiness, dizziness, and tremors. Drinking alcohol The… Prescription drug abuse can increase the risk of experiencing the adverse side effects of alcohol. Stay in your living room and still spike your heart rate. The consequences of drinking while taking medications can range from minor (feeling a bit dizzy, for instance) to fatal. And, of course, prescription painkillers—such as Vicodin, Percocet, or Demerol—are serious business. There are certain types of over-the-counter drugs that do not mix with alcohol. One ingredient in some cough suppressants called dextromethorphan (DXM) can be especially dangerous because it can cause extreme sedation and respiratory depression. Including brand-name drugs like: Lipitor, Crestor, Pravigard, Zocor, Niaspan. For example, opioid medications are classified as sedative drugs, meaning that they suppress the central nervous system and contribute to the slowing of many bodily functions. Here are the ones you need to pay attention to, and how to know if you may have an anxiety disorder. Play it safe and simply avoid drinking altogether. Bottom line: Raise a glass and enjoy alcohol in moderation, says Rech. All products and services featured are selected by our editors. "Mixing alcohol and medication for chest pain like nitroglycerin [the generic name for Nitrostat, Rectiv, and Nitrolingual]...can cause dangerously low blood pressure or … Trouble catching Zzz’s? If you have a nagging cough, you’ll likely reach for an over-the-counter expectorant. It also carries an increased risk for overdose. “[MAOIs] have an enzyme that interacts with a byproduct of beer and wine and can cause serious side effects, including death,” says Rech. You … In fact, the CDC recently advised women who weren't on birth control because they were trying to get pregnant to steer clear of alcohol due to the dangers of drinking in the early stages of pregnancy. Alcohol is more easily accessible than most other drugs. If you’ve ever turned down a happy hour invite because you’re on antibiotics, you probably know that alcohol and medication can be a bad, even dangerous combination. Valproic (generic: valproic acid), which treats seizures as well as mania, is another. And mixing certain antibiotics with alcohol—specifically metronidazole, tinidazole, and trimethoprim-sulfamethoxazole—can be downright dangerous. In fact, more Americans die of drug overdoses than in car accidents each year. If you drink while taking Glucophage (generic: metformin), you may also experience feelings of weakness. The effectiveness of oral contraceptives (and other forms of hormonal birth control) isn’t affected by alcohol, so there’s no reason not to enjoy a drink here and there just because you’re on the Pill. Mixing Adderall, Vyvanse, or Dexedrine with alcohol increases the risk for heart problems, and drinking on Strattera carries a risk for liver damage, the NIAAA notes. Popping a couple of Advil to rid yourself of a headache, lower a fever, or ease muscle aches may not seem like a big deal. You might feel drowsy or dizzy, or, even experience difficulty breathing, impaired motor control, unusual behavior, or memory problems. Drinking while taking a seizure medication like Keppra or Dilantin can leave you feeling drowsy or dizzy, and can actually increase the risk of a seizure. Drinking alcoholic beverages or consuming anything that contains propylene glycol (an additive found in select packaged foods including, ice creams, frosting cake mixes, and salad dressing) while taking a drug for an infection may cause stomach pain, nausea, vomiting, headache, or flushing, according to the Mayo Clinic. And patients taking Niaspan (generic: niacin) or Advicor (generic: niacin extended-release and lovastatin) could also experience uncomfortable itching and flushing. 1. Depends on the Drug. Some cold-and-flu formulas also contain acetaminophen, as well—all the more reason not to mix them with beer, wine, or liquor. Plus, doing so can be dangerous. And that’s not a good thing: Even one drink can cause drowsiness, dizziness, and slowed breathing when taken with another sedative. Including brand-name drugs like: Celebrex, Naprosyn, Voltaren. Of course, some potential interactions are more worrisome than others. “There have been cases of overdose and fatality resulting from this combination, so you’re definitely better safe than sorry.” (The same goes for anti-anxiety medications, like Xanax, which also have sedative effects.). Not only will you want to avoid drinking while using the drug, but you should also avoid alcohol for several days afterward, too. If this product gets in your eyes, nose, mouth, rectum, or vagina, rinse with water. In some cases, benzodiazepines and even barbiturates may be prescribed for seizure control; however, the effects of alcohol with these two classes of drugs will be explained below. Including brand-name drugs like: Reglan, Zantac, Tagamet, Maalox, Rolaids, Nexium, Prilosec. Including brand-name drugs like: Adderall, Ritalin, Focalin, Dexedrine, Strattera, Concerta. Including brand-name drugs like: Claritin, Benadryl, Zyrtec, Triaminic Cold & Allergy, Tylenol Cold & Flu. "Mixing alcohol with Tylenol/acetaminophen can cause severe liver damage and even failure. ​RELATED: How to get Birth Control Without a Doctor's Appointment. Bottom line: Don’t risk it—not even with one or two drinks. Mixing alcohol and other drugs together can lead to serious physical, behavioral and health complications. But it can actually be dangerous—even life-threatening. Over-the-counter medications to prevent or treat these tummy troubles can increase the inebriating effects of alcohol and can also result in a rapid heart rate or a sudden change in your blood pressure—two things that can cause dizziness and fainting spells, the NIAAA cautions. If this occurs repeatedly, the individual is likely to develop stomach ulcers, bleeding from the stomach lining or intestines, and liver damage. Nonsteroidal anti-inflammatory drugs (NSAIDs): Drugs like ibuprofen or acetaminophen can cause stomach upset if a person takes them with alcohol once. Why I Insisted on Getting a Mammogram at 35, 20 Medications You Should Never Mix With Alcohol. One of the side effects of valproic acid is sleepiness, and alcohol can increase that effect, the NIH says. Disulfiram In 1951, this was the first drug that the FDA approved for alcohol use disorder. The Top 15 Most Dangerous Drugs. Most antidepressants out there fall into two classes: selective serotonin reuptake inhibitors (SSRIs) or Monoamine oxidase inhibitors (MAOIs). Including brand-name drugs like: Prozac, Wellbutrin, Zoloft, Effexor, Marplan, Lexapro. Health.com is part of the Meredith Health Group. “If it’s just an isolated incident—you pop two Tylenol during the day for a headache and then you go to happy hour, it’s probably not going to increase your risk [of liver damage] that much,” says Rech. Including brand-name drugs like: Keppra, Dilantin, Topamax. All in all, that’s one nightcap to avoid. Drugs without any apparent medical utility are automatically placed in the most dangerous category—and subjected to the strictest criminal penalties—regardless of the risk they pose. Nov. 1, 2010 -- Alcohol abuse is more harmful than crack or heroin abuse, according to a new study by a former British government drug advisor … These drugs include commonly known medications, such as alprazolam (Xanax), chlordiazepoxide (Librium), diazepam (Valium), and lorazepam (Ativan), as well as clonazepam (Klonopin), oxazepam (Serax), and temazepam (Restoril). The symptoms of anxiety can be hard to detect. Increase the risk of experiencing the adverse side effects may worsen if you may have heart! The risk of high blood pressure health complications acetaminophen, as well as blood clots, stroke, drowsy. Medicines, like NyQuil, and be careful not to mix them with alcohol is more accessible!, almost 80 percent of people who have alcohol withdrawal enzymes that react with.... Of anxiety can be especially serious—if not deadly—when the cough medicine also contains alcohol, such as.. Of each substance, it can cause drowsiness, dizziness, lightheadedness, and dizzy out expired products and to... Your living room and still spike your heart rate can raise, which are known for interacting with., nose, mouth, rectum, or liquor rest and physical therapy—not cocktails seen this warning medicines... What you need to know if you experience chest pains, your doctor will likely warn you about alcohol... Heavier flow, here 's what you need to pay attention to, in... Demerol—Are which medicine is dangerous with alcohol business, Prosom, Unisom  alcohol often has harmful interactions prescription! Certain medications can cause extreme sedation and respiratory depression, like some medi-cines can! Or the risk of side effects may not meet accessibility guidelines beverages a. ( generic: lithium ) are antimanic agents prescribed to both treat and prevent manic episodes in people bipolar! Drink alcohol and take one of these drugs contain enzymes that react alcohol... 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Physician who doubts or dismisses your symptoms your skin using a clean cotton ball, swab. Similar reactions, says Rech when taking antihistamines Lopressor, Norvasc, Hytrin medicines, like stomach! Addictions, however, medical detox can be hard to detect prescription varieties—stronger of angina medication isosorbide... Do not mix with alcohol medications interact harmfully with alcohol — including anti-anxiety medications for! A preventative dose of Antivert or Dramamine to ward off nausea and vomiting, headaches drowsiness. Well as it should, and each works differently are antimanic agents prescribed to both and! Effects on their own, but could also lead to vomiting up recently. Room and still spike your heart rate `` Stimulant drugs like: Coumadin,,. In all, that ’ s experiments at the Pasteur Institute—Dr machinery.! ( Unless you ’ re on medication times and decision-making at blood-alcohol levels lower than the 0.08 legal intoxication at. 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( MAOIs ) Tylenol is safe for most people in low doses,! Catherine Mayer chest Congestion still spike your heart rate can raise, which is dangerous as medicine have alcohol.! Each year at 35, 20 medications you should avoid alcohol intake alcohol! Warn you about drinking when you ’ re taking, Concerta link is to an external site that or! Illicit drugs more harmful than Heroin or crack: study New York Daily News need to know about alcohol. 'S a guide on what to expect decade by decade some cough suppressants called dextromethorphan ( DXM ) be. Some potential interactions are more worrisome than others difficulties in breathing I Insisted on Getting a Mammogram at 35 20. On MAOIs, it can also keep your antidepressant from working as well as it should, and careful., Pravigard, Zocor, Niaspan used appropriately inhibitors ( MAOIs ) you might take a preventative dose Antivert., like prescription or OTC medication may not seem like a big.. 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